Anti-inflammatory activity of 9-hydroxycanthin-6-one extracted from hairy-root cultures of Eurycoma longifolia potentially via aryl hydrocarbon receptor induction

Keywords: Aryl hydrocarbon receptor, Eurycoma longifolia, 9-Hydroxycanthin-6-one, Inflammatory cytokines
DOI: 10.3329/bjp.v17i3.60373

References

Bhat R, Karim AA. Tongkat Ali (Eurycoma longifolia Jack): A review on its ethnobotany and pharmacological importance. Fitoterapia 2010; 81: 669-79.

Kimura A, Naka T, Nakahama T, Chinen I, Masuda K, Nohara K, Fujii-Kuriyama Y, Kishimoto T. Aryl hydrocarbon receptor in combination with Stat1 regulates LPS-induced inflammatory responses. J Exp Med. 2009; 206: 2027-35.

Masuda K, Kimura A, Hanieh H, Nguyen NT, Nakahama T, Chinen I, Otoyo Y, Murotani T, Yamatodani A, Kishimoto T. Aryl hydrocarbon receptor negatively regulates LPS-induced IL-6 production through suppression of histamine production in macrophages. Int Immunol. 2011; 23: 637-45.

Neavin DR, Liu D, Ray B, Weinshilboum RM. The role of the aryl hydrocarbon receptor (AHR) in immune and inflammatory Diseases. Int J Mol Sci. 2018; 19: E3851.

Ngoc PB, Pham TB, Nguyen HD, Tran TT, Chu HH, Chau VM, Lee JH, Nguyen TD. A new anti-inflammatory β-carboline alkaloid from the hairy-root cultures of Eurycoma longifolia. Nat Prod Res. 2016; 30: 1360-65.

Nguyen HD, Choo YY, Nguyen TD, Nguyen HN, Chau VM, Lee JH. 7-Methoxy-(9H-β-carbolin-1-il)-(E)-1-propenoic acid, a β-carboline alkaloid from Eurycoma longifolia, exhibits anti-inflammatory effects by activating the Nrf2/heme oxygenase-1 pathway. J Cell Biochem. 2016; 117: 659-70.

Rehman SU, Choe K, Yoo HH. Review on a Traditional Herbal Medicine, Eurycoma longifolia Jack (Tongkat Ali): Its traditional uses, chemistry, evidence-based pharmacology and toxicology. Molecules 2016; 21: 331.

Rehman SU, Choe K, Yoo HH. Review on a traditional herbal medicine, Eurycoma longifolia Jack (Tongkat Ali): Its traditional uses, chemistry, evidence-based pharmacology and toxicology. Molecules 2016; 21: 331.

Tong KL, Chan KL, AbuBakar S, Low BS, Ma HQ, Wong PF. The in vitro and in vivo anti-cancer activities of a standardized quassinoids composition from Eurycoma longifolia on LNCaP human prostate cancer cells. PLoS One. 2015; 10: e0121752.

Zhu J, Luo L, Tian L, Yin S, Ma X, Cheng S, Tang W, Yu J, Ma W, Zhou X, Fan X, Yang X, Yan J, Xu X, Lv C, Liang H. Aryl hydrocarbon receptor promotes IL-10 expression in inflammatory macrophages through Src-STAT3 signaling pathway. Front Immunol. 2018; 9: 2033.

Published
2022-09-11

Apply citation style format of Bangladesh Journal of Pharmacology

Section
Letter to the Editor
Financial Support
Graduate University of Science and Technology, Vietnam Academy of Science and Technology (grant code: GUST.STS.ĐT2019-SH01)
Conflict of Interest
Authors declare no conflict of interest